Endocrine Abstracts

Carcinomas are the third most frequent cause of complications in acromegalic patients. It has been suggested that diabetes potentiates the risk of cancer. To assess the frequency and type of malignant neoplasms in acromegalic patients and control group; to evaluate, in both groups, the relationship between IGF-I/GH and the development of cancer, and between glucose metabolism and cancer in two centers of Buenos Aires, Argentina. Retrospective, cross-sectional study; medical re...

Giant prolactinomas are tumors with a large size >4 cm and/or prolactin levels higher than 3000 ng/ml and/or highly invasive growth. Today dopamine agonists (DA), mainly cabergoline (CAB), are the first-line choice in the treatment of these tumorsTo assess the efficacy, safety and long-term follow-up of patients with giant prolactinomas treated with DA. We retrospectively reviewed the clinical records of 33 patients with giant prolactinomas. Mea...